The Noncoding RNA Taurine Upregulated Gene 1 Is Required for Differentiation of the Murine Retina

@article{Young2005TheNR,
  title={The Noncoding RNA Taurine Upregulated Gene 1 Is Required for Differentiation of the Murine Retina},
  author={Terri L Young and Takahiko Matsuda and Constance L. Cepko},
  journal={Current Biology},
  year={2005},
  volume={15},
  pages={501-512}
}
BACKGROUND With the advent of genome-wide analyses, it is becoming evident that a large number of noncoding RNAs (ncRNAs) are expressed in vertebrates. However, of the thousands of ncRNAs identified, the functions of relatively few have been established. RESULTS In a screen for genes upregulated by taurine in developing retinal cells, we identified a gene that appears to be a ncRNA. Taurine Upregulated Gene 1 (TUG1) is a spliced, polyadenylated RNA that does not encode any open reading frame… CONTINUE READING
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