The Non-Coding Oncogene: A Case of Missing DNA Evidence?

Abstract

The evidence that links classical protein-coding proto-oncogenes and tumor suppressors, such as MYC, RAS, P53, and RB, to carcinogenesis is indisputable. Multiple lines of proof show how random somatic genomic alteration of such genes (e.g., mutation, deletion, or amplification), followed by selection and clonal expansion, forms the main molecular basis of… (More)
DOI: 10.3389/fgene.2012.00170

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@inproceedings{Shahrouki2012TheNO, title={The Non-Coding Oncogene: A Case of Missing DNA Evidence?}, author={Puja Shahrouki and Erik Larsson}, booktitle={Front. Gene.}, year={2012} }