The Nobel Chronicles

@article{Raju1998TheNC,
  title={The Nobel Chronicles},
  author={Tonse N. K. Raju},
  journal={The Lancet},
  year={1998},
  volume={352}
}
  • T. Raju
  • Published 24 October 1998
  • Philosophy
  • The Lancet

Lactate in the Tumor Microenvironment: An Essential Molecule in Cancer Progression and Treatment

TLDR
The existing literature on lactate metabolism in tumor cells and the ability of extracellular lactate to direct the metabolic reprogramming of those cells are reviewed and the efforts to target the lactate production and its transport as a promising approach for cancer therapeutics are explored.

Invited review: Quantifying proton exchange from chemical reactions - Implications for the biochemistry of metabolic acidosis.

  • R. Robergs
  • Chemistry, Biology
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology
  • 2019

Biochemistry of exercise-induced metabolic acidosis.

TLDR
This review presents clear evidence that there is no biochemical support for lactate production causing acidosis, and there is a wealth of research evidence to show that acidosis is caused by reactions other than lactateproduction.