The Nithsdale Schizophrenia Surveys. XIV: Plasma lipid peroxide and serum vitamin E levels in patients with and without tardive dyskinesia, and in normal subjects.

@article{McCreadie1995TheNS,
  title={The Nithsdale Schizophrenia Surveys. XIV: Plasma lipid peroxide and serum vitamin E levels in patients with and without tardive dyskinesia, and in normal subjects.},
  author={Robin G. McCreadie and E. Macdonald and David Wiles and Glenda Campbell and John R. Paterson},
  journal={The British journal of psychiatry : the journal of mental science},
  year={1995},
  volume={167 5},
  pages={
          610-7
        }
}
BACKGROUND Tardive dyskinesia (TD) may be mediated through free radical damage to neurons. Plasma lipid peroxide levels are a measure of radical damage to fats. Vitamin E is a free radical scavenger. METHOD One hundred and twenty-eight schizophrenic patients were examined for TD using the Abnormal Involuntary Movements Scale. Blood samples were taken to measure plasma lipid peroxide, serum vitamin E and cholesterol, and vitamin E:cholesterol ratios. Twenty-four patients were also examined in… CONTINUE READING