The New Neurometabolic Cascade of Concussion.

@article{Giza2014TheNN,
  title={The New Neurometabolic Cascade of Concussion.},
  author={Christopher C. Giza and David A. Hovda},
  journal={Neurosurgery},
  year={2014},
  volume={75 Suppl 4},
  pages={S24-33}
}
Since the original descriptions of postconcussive pathophysiology, there has been a significant increase in interest and ongoing research to study the biological underpinnings of concussion. The initial ionic flux and glutamate release result in significant energy demands and a period of metabolic crisis for the injured brain. These physiological perturbations can now be linked to clinical characteristics of concussion, including migrainous symptoms, vulnerability to repeat injury, and… CONTINUE READING
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