The New Bacterial Cell Biology: Moving Parts and Subcellular Architecture

@article{Gitai2005TheNB,
  title={The New Bacterial Cell Biology: Moving Parts and Subcellular Architecture},
  author={Zemer Gitai},
  journal={Cell},
  year={2005},
  volume={120},
  pages={577-586}
}
Recent advances have demonstrated that bacterial cells have an exquisitely organized and dynamic subcellular architecture. Like their eukaryotic counterparts, bacteria employ a full complement of cytoskeletal proteins, localize proteins and DNA to specific subcellular addresses at specific times, and use intercellular signaling to coordinate multicellular events. The striking conceptual and molecular similarities between prokaryotic and eukaryotic cell biology thus make bacteria powerful model… Expand
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References

SHOWING 1-10 OF 125 REFERENCES
Dynamic localization of proteins and DNA during a bacterial cell cycle
TLDR
Surprisingly, in this one-micron bacterial cell, the dynamic spatial disposition of regulatory proteins, structural proteins and specific regions of the chromosome are important components of both cell-cycle progression and the generation of daughter cells with different cell fates. Expand
Bacterial Mitotic Machineries
TLDR
It is described how prokaryotic actin homologs form mitotic machineries that segregate DNA before cell division, and evidence from three different laboratories indicate that the morphogenetic MreB protein may be involved in segregation of the bacterial chromosome. Expand
Control of Cell Shape in Bacteria Helical, Actin-like Filaments in Bacillus subtilis
TLDR
The distribution of the proteins in different species of bacteria, and the similarity of their sequence to eukaryotic actins, suggest that the MreB-like proteins have a cytoskeletal, actin-like role in bacterial cell morphogenesis. Expand
Chromosome segregation in Eubacteria.
TLDR
A picture is developing of how bacterial chromosomes are organized within the cell, how they are separated following duplication, and how these processes are coordinated with the cell cycle. Expand
Bacterial Chromosome Dynamics
TLDR
The principles that underlie chromosome segregation in bacteria and eukaryotes share similarities, although bacteria segregate DNA as it replicates and lack a eukARYote-like mitotic apparatus for segregating chromosomes. Expand
Molecules of the bacterial cytoskeleton.
The structural elucidation of clear but distant homologs of actin and tubulin in bacteria and GFP labeling of these proteins promises to reinvigorate the field of prokaryotic cell biology. FtsZ (theExpand
Bacterial cell division and the Z ring.
TLDR
Evidence suggests that the Z ring is utilized by all prokaryotic organisms for division and may also be used by some eukaryotic organelles. Expand
A Microdomain for Protein Secretion in Gram-Positive Bacteria
TLDR
This work has discovered that protein secretion by way of the general secretory pathway in the important human pathogen Streptococcus pyogenes proceeds through a single microdomain, which may represent a paradigm for secretion common to other Gram-positive pathogens with profound implications for pathogenesis. Expand
The Bacterial Cytoskeleton An Intermediate Filament-Like Function in Cell Shape
TLDR
A bacterial equivalent to IF proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus and it is proposed that IF-like filaments of c Crescentin assemble into a helical structure, which by applying its geometry to the cell, generates a vibrioids or helical cell shape depending on the length of the cell. Expand
Dynamic compartmentalization of bacteria: accurate division in E. coli.
TLDR
This model spontaneously generates protein oscillations in good agreement with experiments and explores the oscillation stability, frequency, and wavelength as a function of protein concentration and bacterial length. Expand
...
1
2
3
4
5
...