Genetic signature of disease epizootic and reintroduction history in an endangered carnivore
- Environmental ScienceJournal of Mammalogy
The results suggest the importance of early and sustained management in mitigating disease epizootics in naïve populations for the maintenance of genetic diversity and the impacts of a novel pathogen on genetic diversity in a genetically depauperate endangered species.
Toward an Evolutionarily Appropriate Null Model: Jointly Inferring Demography and Purifying Selection
This work investigates how population size changes and the strength of purifying selection affect patterns of variation at “neutral” sites near functional genomic components, and proposes a novel statistical framework for jointly inferring the contribution of the relevant selective and demographic parameters.
The Rate of Molecular Evolution When Mutation May Not Be Weak
A direct and transparent theoretical analysis of the Wright-Fisher model of population genetics shows that some of the most important rules of molecular evolution are fundamentally changed by considering recurrent mutation's full e↵ect.
Stochasticity in cultural evolution: a revolution yet to happen
- SociologyHistory and philosophy of the life sciences
It is argued that current evolutionary accounts of cultural change are limited because they do not adopt a systematic stochastic approach, and that the field of cultural evolution would benefit from a Stochastic revolution.
Population size and time since island isolation determine genetic diversity loss in insular frog populations
- Environmental Science, BiologyMolecular ecology
The results suggest that decreased genetic diversity and genetic differentiations among insular populations may have been caused by random genetic drift following isolation by rising sea levels during the Holocene.
Estimating the Distribution of Selection Coefficients from Phylogenetic Data Using Sitewise Mutation-Selection Models
A sitewise mutation–selection phylogenetic model is used to estimate the distribution of selection coefficients among novel and fixed mutations (substitutions) in a data set of 244 mammalian mitochondrial genomes and a set of 401 PB2 proteins from influenza to find a bimodal distribution with a small mode of advantageous mutations.
Neutrality in evolutionary algorithms… What do we know?
- Computer ScienceEvol. Syst.
This article provides a general overview on the work carried out on neutrality in EAs using as a framework the origin of neutrality and its study in different paradigms of EAs (e.g., Genetic Algorithms, Genetic Programming).
The degeneration of Y chromosomes.
- BiologyPhilosophical transactions of the Royal Society of London. Series B, Biological sciences
The results suggest that the effective population sizes of evolving Y or neo-Y chromosomes are severely reduced, as expected if some or all of the hypothesized processes leading to degeneration are operative.
A New Likelihood-based Test for Natural Selection
It is suggested that ρ will be a useful tool for identifying genomic regions that may be subject to natural selection and can directly incorporate a null hypothesis reflecting general demographic histories.
MEGA11: Molecular Evolutionary Genetics Analysis Version 11
- Biology, Computer ScienceMolecular biology and evolution
New additions are described that make MEGA a more comprehensive tool for building timetrees of species, pathogens, and gene families using rapid relaxed-clock methods and a Bayesian method for estimating neutral evolutionary probabilities of alleles in a species using multispecies sequence alignments.