The Neurospora crassa exocyst complex tethers Spitzenkörper vesicles to the apical plasma membrane during polarized growth

@inproceedings{Riquelmea2014TheNC,
  title={The Neurospora crassa exocyst complex tethers Spitzenk{\"o}rper vesicles to the apical plasma membrane during polarized growth},
  author={Meritxell Riquelmea and Erin L. Bredewegb and Olga Callejas-Negretea and Robert W. Robersonc and Sarah Ludwigd and Alejandro Beltr{\'a}n-Aguilara and Stephan Seilerd and Peter Novicke and Michael Freitagb},
  year={2014}
}
  • Meritxell Riquelmea, Erin L. Bredewegb, +6 authors Michael Freitagb
  • Published 2014
Fungal hyphae are among the most highly polarized cells. Hyphal polarized growth is supported by tip-directed transport of secretory vesicles, which accumulate temporarily in a stratified manner in an apical vesicle cluster, the Spitzenkörper. The exocyst complex is required for tethering of secretory vesicles to the apical plasma membrane. We determined that the presence of an octameric exocyst complex is required for the formation of a functional Spitzenkörper and maintenance of regular… CONTINUE READING