The Neuropsychiatric Inventory
@article{Cummings1997TheNI, title={The Neuropsychiatric Inventory}, author={Jeffrey L. Cummings}, journal={Neurology}, year={1997}, volume={48}, pages={10S - 16S} }
The Neuropsychiatric Inventory (NPI) was developed to assess psychopathology in dementia patients. [] Key Method It evaluates 12 neuropsychiatric disturbances common in dementia: delusions, hallucinations, agitation, dysphoria, anxiety, apathy, irritability, euphoria, disinhibition, aberrant motor behavior, night-time behavior disturbances, and appetite and eating abnormalities.
1,348 Citations
Neuropsychiatric assessment of Alzheimer’s disease and related dementias
- Psychology, MedicineAging
- 2001
The NPI is a valid and reliable means of assessing neuropsychiatric symptoms in patients with dementia and correlates with increasing disability in activities of daily living and increasing cognitive impairment.
Neuropsychiatric Symptoms of Alzheimer’s Disease in Down Syndrome and Its Impact on Caregiver Distress
- Medicine, PsychologyJournal of Alzheimer's disease : JAD
- 2021
NPS are frequent and severe in individuals with DS and AD, contributing to caregiver distress, and must be considered of critical relevance demanding management and treatment.
Prevalence and clinical correlates of neuropsychiatric symptoms in dementia
- Psychology, MedicineAmerican journal of Alzheimer's disease and other dementias
- 2005
It is found that neuropsychiatric symptoms were common, with approximately three-fourths of the subjects exhibiting at least one symptom during the preceding month, and frequency and severity of symptoms were similar for the all-dementia and Alzheimer's disease–only groups.
An Itemized Approach to Assessing Behavioral and Psychological Symptoms in Dementia
- PsychologyAmerican journal of Alzheimer's disease and other dementias
- 2009
Results indicate an itemized approach to assessing behavioral and psychological symptoms in dementia among patients with mild-to-moderate dementia can be reliable, has the power to capture multiple features of neuropsychiatric symptoms, and can produce a rich neurobehavioral profile adding valuable information to the diagnosis and treatment of these patients.
Assessment of neuropsychiatric symptoms in dementia: validity and reliability of the Lebanese version of the neuropsychiatric inventory questionnaire
- Psychology, MedicineApplied neuropsychology. Adult
- 2019
The Arabic version of the NPI-Q showed evidence of good psychometric properties indicating that it is a suitable tool for the routine assessment of neuropsychiatric symptoms for Lebanese patients with dementia in clinical settings.
Neuropsychiatric symptom clusters of Alzheimer disease in Hong Kong Chinese: correlates with caregiver burden and depression.
- Psychology, MedicineThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
- 2013
Concurrent validity of neuropsychiatric subgroups on caregiver burden in Alzheimer disease patients.
- Psychology, MedicineThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
- 2008
Neuropsychiatric subgroups were able to differentially predict caregiver burden and appear to lend further support to the validity of classifying neuropsychiatric symptoms in AD patients using cluster analysis.
Prevalence, patterns, service needs, and assessment of neuropsychiatric disorders among people with epilepsy in residential care: Validation of the Neuropsychiatric Inventory as a caregiver-rated measure of neuropsychiatric functioning in epilepsy
- Psychology, MedicineEpilepsy & Behavior
- 2008
The reliability and validity of the Turkish version of the Neuropsychiatric Inventory-Clinician.
- Psychology, MedicineTurkish journal of medical sciences
- 2015
The Turkish version of the NPI-C scale was found to be a reliable and valid instrument to assess neuropsychiatric symptoms in Turkish elderly subjects with AD.
Neuropsychiatric inventory workshop: behavioral and psychologic symptoms of dementia in Asia.
- Psychology, MedicineAlzheimer disease and associated disorders
- 2006
The NPI was the subject of a workshop in Asia in conjunction with the International Workgroup on Dementia Drug Guidelines and investigators using the NPI from 4 Asian areas presented conclusions from their research.
References
SHOWING 1-10 OF 80 REFERENCES
The Neuropsychiatric Inventory
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- 1994
The NPI has the advantages of evaluating a wider range of psychopathology than existing instruments, soliciting information that may distinguish among different etiologies of dementia, differentiating between severity and frequency of behavioral changes, and minimizing administration time.
The spectrum of behavioral changes in Alzheimer's disease
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Agitation, dysphoria, apathy, and aberrant motor behavior were significantly correlated with cognitive impairment in patients with Alzheimer's disease compared with normal age-matched control subjects.
Depressive Symptoms in Alzheimer Disease: Assessment and Determinants
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The results suggest that depression in AD is not severe and is unrelated to patient self-awareness of illness, and it is hypothesized that the cholinergic deficit of AD may ameliorate depressive symptoms.
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It is hypothesized that delusions are independent noncognitive manifestations of the neurobiology of AD and MID and that delusional patients are more behaviorally disturbed than those without delusions.
Alzheimer disease and frontotemporal dementias. Behavioral distinctions.
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The Neuropsychiatric Inventory provides a behavioral profile that differentiates patients with FTD from patients with AD, and are more behaviorally disturbed but are often less depressed than patients withAD relative to their level of apathy.
Biologic Markers and Neurochemical Correlates of Agitation and Psychosis in Dementia
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The evidence for biologic and neurochemical correlates of psychosis and agitation in dementia, and the treatment implications for these findings are reviewed.
Effect of Tacrine on Behavioral Symptoms in Alzheimer's Disease: An Open-Label Study
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It is suggested that tacrine may be beneficial for selected behavioral symptoms in AD patients, particularly at higher doses and in those with moderate cognitive deficits.
Psychosis and physical aggression in probable Alzheimer's disease.
- Psychology, MedicineThe American journal of psychiatry
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This study suggests that delusions are a risk factor for physical aggression in patients with probable Alzheimer's disease who have moderate to severe cognitive impairment.
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Information regarding the characteristic phenomenology of the behavioral symptoms studied was used to design a clinical rating instrument for AD patients, the Behavioral Pathology in Alzheimer's Disease Rating Scale (BEHAVE-AD), which should be useful in prospective studies of behavioral symptoms as well as in pharmacologic trials.
Alzheimer's disease with delusions and hallucinations
- Psychology, MedicineNeurology
- 1991
It is demonstrated that AD patients with delusions and hallucinations have a greater degree of cerebral dysfunction and a relatively focal neuropsychological defect, which may indicate a localized pathologic abnormality.