The Neuroprotective Effect of Genetic Mannose-Binding Lectin Deficiency Is Not Sustained in the Subacute Phase of Stroke

Abstract

The complement cascade is a critical mediator of the inflammatory response following cerebral ischemia. Recent work has demonstrated that genetic deficiency of mannose-binding lectin (MBL) ameliorates reperfusion injury and improves outcome in the acute phase of stroke. The present study sought to further delineate the pathogenic role of MBL in stroke and… (More)
DOI: 10.1007/s12975-011-0104-2

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