The Neuropathic Diabetic Foot Ulcer Microbiome Is Associated With Clinical Factors

@inproceedings{Gardner2013TheND,
  title={The Neuropathic Diabetic Foot Ulcer Microbiome Is Associated With Clinical Factors},
  author={Sue E Gardner and Stephen L. Hillis and Kris P Heilmann and Julia A Segre and Elizabeth A. Grice},
  booktitle={Diabetes},
  year={2013}
}
Nonhealing diabetic foot ulcers (DFUs) are a common and costly complication of diabetes. Microbial burden, or "bioburden," is believed to underlie delayed healing, although little is known of those clinical factors that may influence microbial load, diversity, and/or pathogenicity. We profiled the microbiomes of neuropathic nonischemic DFUs without clinical evidence of infection in 52 individuals using high-throughput sequencing of the bacterial 16S ribosomal RNA gene. Comparatively, wound… CONTINUE READING
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