The Neglected Intrinsic Resistome of Bacterial Pathogens

@article{Fajardo2008TheNI,
  title={The Neglected Intrinsic Resistome of Bacterial Pathogens},
  author={Alicia Fajardo and Nadia Martinez-Martin and Mar{\'i}a Guadalupe Mercadillo and Juan Carlos Gal{\'a}n and Bart Ghysels and S. J. B. A. Hoppenbrouwers Radboud University Nijmege Matthijs and Pierre Cornelis and Lutz Wiehlmann and Burkhard T{\"u}mmler and Fernando Baquero and Jos{\'e} L Mart{\'i}nez},
  journal={PLoS ONE},
  year={2008},
  volume={3},
  pages={1376 - 1378}
}
Bacteria with intrinsic resistance to antibiotics are a worrisome health problem. It is widely believed that intrinsic antibiotic resistance of bacterial pathogens is mainly the consequence of cellular impermeability and activity of efflux pumps. However, the analysis of transposon-tagged Pseudomonas aeruginosa mutants presented in this article shows that this phenotype emerges from the action of numerous proteins from all functional categories. Mutations in some genes make P. aeruginosa more… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 8 times over the past 90 days. VIEW TWEETS
87 Citations
47 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 87 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 47 references

Handbook of Microbiological Media; Parks LC, editor

  • RM Atlas
  • 1993
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…