The Neandertal genome and ancient DNA authenticity

@article{Green2009TheNG,
  title={The Neandertal genome and ancient DNA authenticity},
  author={Richard E. Green and Adrian W. Briggs and Johannes Krause and Kay Pr{\"u}fer and Hern{\'a}n A. Burbano and Michael F. Siebauer and Michael Lachmann and Svante P{\"a}{\"a}bo},
  journal={The EMBO Journal},
  year={2009},
  volume={28},
  pages={2494 - 2502}
}
Recent advances in high‐thoughput DNA sequencing have made genome‐scale analyses of genomes of extinct organisms possible. With these new opportunities come new difficulties in assessing the authenticity of the DNA sequences retrieved. We discuss how these difficulties can be addressed, particularly with regard to analyses of the Neandertal genome. We argue that only direct assays of DNA sequence positions in which Neandertals differ from all contemporary humans can serve as a reliable means to… 
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