The Nature & Role of Mucosal Damage in Relation to Salmonella Typhimurium-induced Fluid Secretion in the Rabbit Ileum

@article{Wallis1986TheN,
  title={The Nature & Role of Mucosal Damage in Relation to Salmonella Typhimurium-induced Fluid Secretion in the Rabbit Ileum},
  author={Timothy S. Wallis and William G. Starkey and J Fey Stephen and S J Haddon and Megan P. H. Osborne and David C. A Candy},
  journal={Pediatric Research},
  year={1986},
  volume={20},
  pages={691-691}
}
The time course and nature of mucosal damage induced by two human strains of Salmonella typhimurium (TML and W118)in rabbit ileal loops was assessed by scanning and electron microscopy. Fluid secretion was measured by ml fluid accumulated per cm rabbit ileal loop.Salmonella-induced fluid secretion (>0.5ml/cm) occurred in the presence or absence of gross mucosal damage. Neither strain induced mucosal ulceration. When damage did occur it involved shortening of villi by loss of tip regions invaded… CONTINUE READING

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