The Na(+)/H(+) exchanger regulatory factor 2 mediates phosphorylation of serum- and glucocorticoid-induced protein kinase 1 by 3-phosphoinositide-dependent protein kinase 1.

@article{Chun2002TheNE,
  title={The Na(+)/H(+) exchanger regulatory factor 2 mediates phosphorylation of serum- and glucocorticoid-induced protein kinase 1 by 3-phosphoinositide-dependent protein kinase 1.},
  author={Jaesun Chun and Taegun Kwon and Eunjung Lee and Pann-Ghill Suh and Eui-Ju Choi and Sang Sun Kang},
  journal={Biochemical and biophysical research communications},
  year={2002},
  volume={298 2},
  pages={207-15}
}
The Na(+)/H(+) exchanger regulatory factor 2 (NHERF2/TKA-1/E3KARP) contains two PSD-95/Dlg/ZO-1 (PDZ) domains which interact with the PDZ docking motif (X-(S/T)-X-(V/L)) of proteins to mediate the assembly of transmembrane and cytosolic proteins into functional signal transduction complexes. One of the PDZ domains of NHERF2 interacts specifically with the… CONTINUE READING