The NRAMPI, VDR and TNF-alpha gene polymorphisms in Iranian tuberculosis patients: the study on host susceptibility.

@article{Merza2009TheNV,
  title={The NRAMPI, VDR and TNF-alpha gene polymorphisms in Iranian tuberculosis patients: the study on host susceptibility.},
  author={Muayad Aghali Merza and Parissa Farnia and Sabar Anoosheh and Mohammed Varahram and Mehdi Kazampour and Omid Pajand and Shima Saeif and Mehdi Mirsaeidi and Mohammad Reza Masjedi and Ali Akbar Velayati and Sven Eric Hoffner},
  journal={The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases},
  year={2009},
  volume={13 4},
  pages={
          252-6
        }
}
The natural resistance-associated macrophage protein (NRAMP1), Vitamin-D receptor (VDR) and Tumor necrosis factor (TNF-alpha) have been associated in susceptibility to tuberculosis, but the results have been inconsistent. This study aimed to determine the association of NRAMP1, VDR, and TNF-á variant with development of pulmonary tuberculosis (PTB) among Iranian patients. The single nucleotide polymorphisms (SNPs) at INT4, D543, 3'UTR of NRAMP1 gene, SNPs in restriction sites of BsmI, and FokI… CONTINUE READING

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