The NR2B subtype of NMDA receptor: a potential target for the treatment of alcohol dependence.

@article{Nagy2004TheNS,
  title={The NR2B subtype of NMDA receptor: a potential target for the treatment of alcohol dependence.},
  author={J{\'o}zsef Nagy},
  journal={Current drug targets. CNS and neurological disorders},
  year={2004},
  volume={3 3},
  pages={169-79}
}
  • József Nagy
  • Published 2004 in
    Current drug targets. CNS and neurological…
Ethanol is a small molecule acting on several neurotransmitter systems in the brain. Accumulating evidences suggest that the primary excitatory--i.e. the glutamatergic--neurotransmitter system is a particularly important site of ethanol's action. Several studies showed that ethanol is a potent and selective inhibitor of the N-methyl-D-aspartate (NMDA) receptors and prolonged ethanol exposition leads to a compensatory "up-regulation" of these receptors resulting in enhanced NMDA receptor… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Similar Papers

Loading similar papers…