The NMDA-receptor antagonist ketamine as an unconditioned stimulus in taste aversion learning.

@article{Aguado1997TheNA,
  title={The NMDA-receptor antagonist ketamine as an unconditioned stimulus in taste aversion learning.},
  author={Luis Quevedo Aguado and Robert Del Valle and L P{\'e}rez},
  journal={Neurobiology of learning and memory},
  year={1997},
  volume={68 2},
  pages={189-96}
}
Three experiments studied the effectiveness of ketamine acting as an aversive unconditioned stimulus (UCS) in a conditioned flavor aversion procedure. In Experiment 1a, three conditioning trials where sucrose was paired with ketamine produced a weak but significant aversion to sucrose; Experiment 1b showed that this effect was not due to a reduced consumption of sucrose caused by ketamine-induced neophobia. In Experiment 2, acquisition of an aversion to sucrose paired with lithium chloride… CONTINUE READING