The NF-M transcription factor is related to C/EBP beta and plays a role in signal transduction, differentiation and leukemogenesis of avian myelomonocytic cells.

@article{Katz1993TheNT,
  title={The NF-M transcription factor is related to C/EBP beta and plays a role in signal transduction, differentiation and leukemogenesis of avian myelomonocytic cells.},
  author={Sophie Katz and Elisabeth Kowenz-Leutz and Christine M{\"u}ller and K. Meese and Scott A Ness and Achim Leutz},
  journal={The EMBO journal},
  year={1993},
  volume={12 4},
  pages={1321-32}
}
Retroviral oncogenes encode nuclear regulators of gene expression or signal transduction molecules, such as protein kinases, which stimulate the activity of cellular transcription factors. Here we describe the cloning of NF-M, a myeloid-specific transcription factor related to C/EBP beta, which is a target of activated protein kinases. NF-M stimulates the expression of the gene encoding cMGF, a myeloid cell-specific growth factor, creating an autocrine growth loop crucial to oncogene… CONTINUE READING
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