The NF-κB regulatory network

@article{Brasier2007TheNR,
  title={The NF-$\kappa$B regulatory network},
  author={Allan R. Brasier},
  journal={Cardiovascular Toxicology},
  year={2007},
  volume={6},
  pages={111-130}
}
  • A. Brasier
  • Published 2007
  • Biology
  • Cardiovascular Toxicology
Nuclear factor (NF)-κB is a family of seven structurally related transcription factors that play a central role in cardiovascular growth, stress response, and inflammation by controlling gene network expression. Although the NF-κB subunits are ubiquitously expressed, their actions are regulated in a cell-type and stimulus-specific manner, allowing for a diverse spectrum of effects. For example, NF-κB is activated by cytokines, reactive oxygen species, bacterial cell wall products, vasopressors… 
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