The NC1 domain of type XIX collagen inhibits melanoma cell migration.

Abstract

Type XIX collagen is a minor collagen that localizes to basement membrane zones. We previously demonstrated that the C-terminal NC1 domain of type XIX collagen inhibits tumor growth in vivo. In the present study, we analyzed the effects of the NC1(XIX) collagen domain on migratory behaviour of melanoma B16F10 cells. We found that NC1(XIX) do not inhibit… (More)
DOI: 10.1684/ejd.2010.1070

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