The NADPH oxidase of professional phagocytes--prototype of the NOX electron transport chain systems.

@article{Cross2004TheNO,
  title={The NADPH oxidase of professional phagocytes--prototype of the NOX electron transport chain systems.},
  author={Andrew R. Cross and Anthony W Segal},
  journal={Biochimica et biophysica acta},
  year={2004},
  volume={1657 1},
  pages={1-22}
}
The NADPH oxidase is an electron transport chain in "professional" phagocytic cells that transfers electrons from NADPH in the cytoplasm, across the wall of the phagocytic vacuole, to form superoxide. The electron transporting flavocytochrome b is activated by the integrated function of four cytoplasmic proteins. The antimicrobial function of this system… CONTINUE READING