The N-terminal half of membrane CD14 is a functional cellular lipopolysaccharide receptor.

@article{Viriyakosol1996TheNH,
  title={The N-terminal half of membrane CD14 is a functional cellular lipopolysaccharide receptor.},
  author={Suganya Viriyakosol and Theo N. Kirkland},
  journal={Infection and immunity},
  year={1996},
  volume={64 2},
  pages={653-6}
}
CD14, a glycosylphosphatidylinositol-anchored protein on the surface of monocytes, macrophages, and polymorphonuclear leukocytes, is a receptor for lipopolysaccharide (LPS). It was recently reported that an N-terminal 152-amino-acid fragment of soluble CD14 was an active soluble lipopolysaccharide receptor (T. S. -C. Juan, M. J. Kelley, D. A. Johnson, L. A. Busse, E. Hailman, S. D. Wright, and H. S. Lichenstein, J. Biol. Chem. 270:1382-1387, 1995). To determine whether the N-terminal half of… CONTINUE READING

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