The N-terminal domain of OmpATb is required for membrane translocation and pore-forming activity in mycobacteria.

@article{Alahari2007TheND,
  title={The N-terminal domain of OmpATb is required for membrane translocation and pore-forming activity in mycobacteria.},
  author={Anuradha Alahari and Nathalie Saint and Sylvie Campagna and Virginie Molle and G{\'e}rard Molle and Laurent Kremer},
  journal={Journal of bacteriology},
  year={2007},
  volume={189 17},
  pages={6351-8}
}
OmpATb is the prototype of a new family of porins in Mycobacterium tuberculosis and Mycobacterium bovis BCG. Although the pore-forming activity of this protein has been clearly established by using recombinant protein produced in Escherichia coli, characterization of the native porin has been hampered by the scarce amount of protein present in the M. tuberculosis detergent extracts. To this aim, we have developed a protocol to overproduce and obtain high yields of OmpATb in both Mycobacterium… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 36 references

Similar Papers

Loading similar papers…