The N-acylation-phosphodiesterase pathway and cell signalling.

@article{Schmid1996TheNP,
  title={The N-acylation-phosphodiesterase pathway and cell signalling.},
  author={Hellmut Heinrich Schmid and Patr{\'i}cia Cavalcanti Schmid and Vijayalakshmi Natarajan},
  journal={Chemistry and physics of lipids},
  year={1996},
  volume={80 1-2},
  pages={
          133-42
        }
}
Long-chain N-acylethanolamines (NAEs) elicit a variety of biological and pharmacological effects. Anandamide (20:4n-6 NAE) and other polyunsaturated NAEs bind to the cannabinoid receptor and may thus serve as highly specific lipid mediators of cell signalling. NAEs can be formed by phospholipase D-catalyzed hydrolysis of N-acylethanolamine phospholipids or by direct condensation of ethanolamine and fatty acid. So far, most of the latter biosynthetic activity has been shown to be the reverse… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 56 CITATIONS, ESTIMATED 36% COVERAGE

Endocannabinoids: synthesis and degradation.

  • Reviews of physiology, biochemistry and pharmacology
  • 2006
VIEW 5 EXCERPTS
CITES METHODS & BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

1997
2017

CITATION STATISTICS

  • 9 Highly Influenced Citations

Similar Papers