The Mysterious Link between Cholesterol and Alzheimer ’ s Disease : Is the Blood-Brain Barrier a Suspect ?

Abstract

It is now well accepted that the deposition and aggregation of amyloid β (Aβ) peptides are hallmarks of Alzheimer's disease (AD) [1]. These peptides are constitutively secreted by neurons but (for reasons that remain to be established) Aβ metabolism is altered in AD patients and leads slowly to the neurodegenerative process. With these considerations in… (More)

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