The Myoepithelial Cell Layer May Serve As a Potential Trigger Factor for Different Outcomes of Stage-Matched Invasive Lobular and Ductal Breast Cancers

@inproceedings{Hsiao2011TheMC,
  title={The Myoepithelial Cell Layer May Serve As a Potential Trigger Factor for Different Outcomes of Stage-Matched Invasive Lobular and Ductal Breast Cancers},
  author={Yi-Hsuan Hsiao and Horng-Der Tsai and M P Chou and Yan-gao Man},
  booktitle={International journal of biological sciences},
  year={2011}
}
Invasive lobular cancer (ILC) tends to be significantly larger in size with significantly more positive lymph nodes, whereas ILC has a significantly more favorable outcome, compared to stage-matched invasive ductal carcinoma (IDC). The mechanism accounting for such differences remains elusive. Based on morphological, immunohistochemical, and molecular studies of over 1,000 cases of human breast cancers, we hypothesize that the differences may result from the structural and/or functional… CONTINUE READING

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