The Mycobacterium tuberculosis high-affinity iron importer, IrtA, contains an FAD-binding domain.

Abstract

Iron is an essential nutrient not freely available to microorganisms infecting mammals. To overcome iron deficiency, bacteria have evolved various strategies including the synthesis and secretion of high-affinity iron chelators known as siderophores. The siderophores produced and secreted by Mycobacterium tuberculosis, exomycobactins, compete for iron with… (More)
DOI: 10.1128/JB.00223-09

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