The Myc oncoprotein as a therapeutic target for human cancer.

  title={The Myc oncoprotein as a therapeutic target for human cancer.},
  author={Marina Fernanda Vita and Marie Engstr{\"o}m Henriksson},
  journal={Seminars in cancer biology},
  volume={16 4},
Myc expression is deregulated in a wide range of human cancers and is often associated with aggressive, poorly differentiated tumors. The Myc protein is a transcription factor that regulates a variety of cellular processes including cell growth and proliferation, cell-cycle progression, transcription, differentiation, apoptosis, and cell motility. Potential strategies that either inhibit the growth promoting effect of Myc and/or activate its pro-apoptotic function are presently being explored… CONTINUE READING

From This Paper

Topics from this paper.
212 Citations
0 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 212 extracted citations

Similar Papers

Loading similar papers…