The Multiple Sclerosis Impact Scale (MSIS-29): a new patient-based outcome measure.

  title={The Multiple Sclerosis Impact Scale (MSIS-29): a new patient-based outcome measure.},
  author={Jeremy Charles Hobart and Donna L. Lamping and Ray Fitzpatrick and Afsane Riazi and Alan J. Thompson},
  journal={Brain : a journal of neurology},
  volume={124 Pt 5},
Changes in health policy have underlined the importance of evidence-based clinical practice and rigorous evaluation of patient-based outcomes. As patient-based outcome measurement is particularly important in treatment trials of multiple sclerosis, a number of disease-specific instruments have been developed recently. One limitation of these instruments is that none was developed using the standard psychometric approach of reducing a large item pool generated from people with multiple sclerosis… CONTINUE READING
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