The MscS-like channel YnaI has a gating mechanism based on flexible pore helices

@article{Flegler2020TheMC,
  title={The MscS-like channel YnaI has a gating mechanism based on flexible pore helices},
  author={Vanessa Judith Flegler and Akiko Rasmussen and Shanlin Rao and Na Wu and Renato Zenobi and Mark S. P. Sansom and Rainer Hedrich and Tim Rasmussen and Bettina B{\"o}ttcher},
  journal={Proceedings of the National Academy of Sciences},
  year={2020},
  volume={117},
  pages={28754 - 28762}
}
Significance Many biological processes are based on mechanosensitive channels which are stimulated by mechanical forces. In cell-walled organisms, the large family of MscS-like channels is extremely diverse and often several different versions of these channels are present in the same organism. However, we hardly understand the reason for this diversity because only the simplest known member of this family, MscS, has been studied in some depth. Here, we present the molecular structures of two… 
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