The Monro–Kellie hypothesis

  title={The Monro–Kellie hypothesis},
  author={Bahram Mokri},
  pages={1746 - 1748}
  • B. Mokri
  • Published 26 June 2001
  • Medicine
  • Neurology
More than two centuries ago, Alexander Monro applied some of the principles of physics to the intracranial contents and for the first time hypothesized that the blood circulating in the cranium was of constant volume at all times. This hypothesis was supported by experiments by Kellie. In its original form, the hypothesis had shortcomings that prompted modification by others. What finally came to be known as the Monro–Kellie doctrine, or hypothesis, is that the sum of volumes of brain, CSF, and… 
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  • A. Salma
  • Medicine, Psychology
    Child's Nervous System
  • 2014
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The hypothesis that the skull and bony coverings of the vertebral canal form a rigid container for the central nervous system has occupied the attention of anatomists, physiologists and neurologists since its original promulgation by Alexander Monro1 in 1783.
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The Monro clan belonged to the Munro clan from northeast Scotland, and they represented the second, third and fourth generation of a remarkable medical family in Great Britain — a piece of medical history spanning over 300 years.
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We studied a patient with spontaneous intracranial hypotension whose gadolinium-enhanced MRI revealed an extraordinary degree of dural enhancement and striking displacement of the optic chiasm,
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Dr. Wright-St Clair, a New Zealander, has performed a splendid service in depicting the doctors Monro of Edinburgh, paying special attention to five generations of physicians, from John (1670-1740) through the three Alexanders (1697-1859) to David (1813-1877).
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  • Psychology
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The emancipation of the mind from the despotic influence of great names is always a difficult and sometimes a very delicate task. There prevails so natural a feeling of veneration and gratitude for
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Middle cerebral artery pial territory infarcts: A study of the lausanne stroke registry
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Hypothesis: impaired clearance is an important link (washout) between hypoperfusion, embolism, and ischemic stroke
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  • 1998
Doctors Monro: a medical saga. London: The Wellcome Historical Medical Library
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