The Mom1AKR intestinal tumor resistance region consists of Pla2g2a and a locus distal to D4Mit64

Abstract

The Mom1 (Modifier of Min-1) region of distal chromosome 4 was identified during a screen for polymorphic modifiers of intestinal tumorigenesis in ApcMin/+ mice. Here, we demonstrate that the Mom1AKR allele consists of two genetic components. These include the secretory phospholipase Pla2g2a, whose candidacy as a Mom1 resistance modifier has now been tested… (More)
DOI: 10.1038/sj.onc.1203646

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