The Molecular Signatures Database (MSigDB) hallmark gene set collection.

@article{Liberzon2015TheMS,
  title={The Molecular Signatures Database (MSigDB) hallmark gene set collection.},
  author={Arthur Liberzon and Chet Birger and Helga Thorvaldsd{\'o}ttir and Mahmoud Ghandi and Jill P. Mesirov and Pablo Tamayo},
  journal={Cell systems},
  year={2015},
  volume={1 6},
  pages={
          417-425
        }
}
The Molecular Signatures Database (MSigDB) is one of the most widely used and comprehensive databases of gene sets for performing gene set enrichment analysis. Since its creation, MSigDB has grown beyond its roots in metabolic disease and cancer to include >10,000 gene sets. These better represent a wider range of biological processes and diseases, but the utility of the database is reduced by increased redundancy across, and heterogeneity within, gene sets. To address this challenge, here we… CONTINUE READING

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