Regulators of the cytoplasmic dynein motor
- BiologyNature Reviews Molecular Cell Biology
It is found that a single cytoplasmic dynein (a minus end-directed microtubule motor) carries out similarly diverse transport activities as the many different types of kinesin.
Cargo Transport: Two Motors Are Sometimes Better Than One
- BiologyCurrent Biology
Kinesin superfamily motor proteins and intracellular transport
- Biology, ChemistryNature Reviews Molecular Cell Biology
The mechanisms by which different kinesin recognize and bind to specific cargos, as well as how kinesins unload cargo and determine the direction of transport, have now been identified and open exciting new areas of kinesIn research.
Molecular Motors in Plant Cells
plant molecular motors, their function, and regulation with emphasis on model plant Arabidopsis, which has the largest number of kinesins as compared to other multicellular organisms including humans, suggesting that the kinesin superfamily is expanded considerably in plants.
Myosin-driven transport network in plants is functionally robust and distinctive
- BiologyProceedings of the National Academy of Sciences
The Kurth et al. paper shows that the green branch of the tree of life has evolved a very dense and largely unique endomembrane transport network empowered by myosins XI, which is well recognized that long-range cargo transport is actin-centric in fungal and plant cells but mostly relies on microtubule-based motors in vertebrates.
Evolution of the Molecules Coupling mRNA Transport with Translational Control in Metazoans
This chapter reviews recent discoveries sheading light on the evolution of one of the best-characterized machineries that couples transport and translation of mRNAs in metazoans, namely the Drosophila Bic-D/Egl/Dyn RNA localization machinery.
Light-controlled intracellular transport in Caenorhabditis elegans
- BiologyCurrent Biology
SHOWING 1-10 OF 149 REFERENCES
Kinesin and dynein superfamily proteins and the mechanism of organelle transport.
- Biology, ChemistryScience
This review focuses on the molecular mechanism of organelle transport in cells and describes kinesin and dynein superfamily proteins.
Analysis of the myosins encoded in the recently completed Arabidopsis thaliana genome sequence
- Biology, Environmental ScienceGenome Biology
The number of myosins is small overall in Arabidopsis compared with the other sequenced eukaryotic genomes, and exon/intron data suggest that the myosin are highly conserved and that some may be a result of gene duplication.
The way things move: looking under the hood of molecular motor proteins.
The microtubule-based kinesin motors and actin-based myosin motors generate motions associated with intracellular trafficking, cell division, and muscle contraction using a common core structure and convert energy from adenosine triphosphate into protein motion using a similar conformational change strategy.
Kinesin motors and microtubule-based organelle transport in Dictyostelium discoideum
- BiologyJournal of Muscle Research & Cell Motility
The known kinesin and dynein genes in Dictyostelium are described and how the biological functions of these motors has been dissected through a combination of biochemical to genetic approaches are described.
The design plan of kinesin motors.
- BiologyAnnual review of cell and developmental biology
Structural features common to all kinesin motors, as well as specialized features that enable subfamilies of related motors to carry out specialized activities, are discussed.
Kinesins in the Arabidopsis genome: A comparative analysis among eukaryotes
- BiologyBMC Genomics
There are groups of Arabidopsis kinesins that are not present in yeast, Caenorhabditis elegans and Drosophila melanogaster that may, therefore, represent new subfamilies specific to plants and provide clues about their functions in cellular processes.
Kinesin-related gene unc-104 is required for axonal transport of synaptic vesicles in C. elegans
Reconstitution of Membrane Transport Powered by a Novel Dimeric Kinesin Motor of the Unc104/Kif1a Family Purified from Dictyostelium
- BiologyThe Journal of cell biology
Two polypeptides from Dictyostelium extracts are purified and found to be kinesin motors, and the 245-kD protein (DdUnc104) is a close relative of Caenorhabditis elegans Unc104 and mouse KIF1A, neuron-specific motors that deliver synaptic vesicle precursors to nerve terminals.