The Molecular Evolution of the Qo Motif

  title={The Molecular Evolution of the Qo Motif},
  author={Wei-Chun Kao and Carola Hunte},
  booktitle={Genome biology and evolution},
Quinol oxidation in the catalytic quinol oxidation site (Q(o) site) of cytochrome (cyt) bc(1) complexes is the key step of the Q cycle mechanism, which laid the ground for Mitchell's chemiosmotic theory of energy conversion. Bifurcated electron transfer upon quinol oxidation enables proton uptake and release on opposite membrane sides, thus generating a proton gradient that fuels ATP synthesis in cellular respiration and photosynthesis. The Q(o) site architecture formed by cyt b and Rieske iron… CONTINUE READING