The Molecular Biology and Pathophysiology of Vascular Calcification

@article{Mccarty2014TheMB,
  title={The Molecular Biology and Pathophysiology of Vascular Calcification},
  author={Mark F. Mccarty and James J. DiNicolantonio},
  journal={Postgraduate Medicine},
  year={2014},
  volume={126},
  pages={54 - 64}
}
Abstract Vascular calcification (VC), commonly encountered in renal failure, diabetes, and aging, is associated with a large increase in the risk for cardiovascular events and mortality. Calcification of the arterial media and of heart valves clearly plays a mediating role in this regard, whereas it is less clear how calcification of plaque influences atherogenesis and risk for plaque rupture. Vascular calcification is an active process in which vascular smooth muscle cells (VSMCs) adopt an… Expand
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