The Molecular Basis of Ligand Interaction at Free Fatty Acid Receptor 4 (FFA4/GPR120)*

Abstract

The long-chain fatty acid receptor FFA4 (previously GPR120) is receiving substantial interest as a novel target for the treatment of metabolic and inflammatory disease. This study examines for the first time the detailed mode of binding of both long-chain fatty acid and synthetic agonist ligands at FFA4 by integrating molecular modeling, receptor… (More)
DOI: 10.1074/jbc.M114.561449

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Cite this paper

@inproceedings{Hudson2014TheMB, title={The Molecular Basis of Ligand Interaction at Free Fatty Acid Receptor 4 (FFA4/GPR120)*}, author={Brian D. Hudson and Bharat Shimpukade and Graeme Milligan and Trond Ulven}, booktitle={The Journal of biological chemistry}, year={2014} }