The Mode of Action of the Bacillus thuringiensis Vegetative Insecticidal Protein Vip 3 A Differs from That of Cry 1 Ab-Endotoxin

Abstract

The Vip3A protein, secreted by Bacillus spp. during the vegetative stage of growth, represents a new family of insecticidal proteins. In our investigation of the mode of action of Vip3A, the 88-kDa Vip3A full-length toxin (Vip3A-F) was proteolytically activated to an approximately 62-kDa core toxin either by trypsin (Vip3A-T) or lepidopteran gut juice… (More)

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