The Missing Link: How Exosomes and miRNAs can Help in Bridging Psychiatry and Molecular Biology in the Context of Depression, Bipolar Disorder and Schizophrenia

@article{Gruzdev2019TheML,
  title={The Missing Link: How Exosomes and miRNAs can Help in Bridging Psychiatry and Molecular Biology in the Context of Depression, Bipolar Disorder and Schizophrenia},
  author={S. K. Gruzdev and Alexander A. Yakovlev and T. A. Druzhkova and Alla B. Guekht and Natalia V. Gulyaeva},
  journal={Cellular and Molecular Neurobiology},
  year={2019},
  volume={39},
  pages={729-750}
}
MicroRNAs (miRNAs) only recently have been recognized as promising molecules for both fundamental and clinical neuroscience. We provide a literature review of miRNA biomarker studies in three most prominent psychiatric disorders (depression, bipolar disorder and schizophrenia) with the particular focus on depression due to its social and healthcare importance. Our search resulted in 191 unique miRNAs across 35 human studies measuring miRNA levels in blood, serum or plasma. 30 miRNAs replicated… CONTINUE READING

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