The Microbiota Is Essential for the Generation of Black Tea Theaflavins-Derived Metabolites

@inproceedings{Chen2012TheMI,
  title={The Microbiota Is Essential for the Generation of Black Tea Theaflavins-Derived Metabolites},
  author={Huadong Chen and Saeed A. Hayek and Javier Rivera Guzman and Nicholas D. Gillitt and Salam Adnan Ibrahim and Christian Jobin and Shengmin Sang},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND Theaflavins including theaflavin (TF), theaflavin-3-gallate (TF3G), theaflavin-3'-gallate (TF3'G), and theaflavin-3,3'-digallate (TFDG), are the most important bioactive polyphenols in black tea. Because of their poor systemic bioavailability, it is still unclear how these compounds can exert their biological functions. The objective of this study is to identify the microbial metabolites of theaflavins in mice and in humans. METHODS AND FINDINGS In the present study, we gavaged… CONTINUE READING

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