The MgATP-dependent protein phosphatase and protein phosphatase 1 have identical substrate specificities.

@article{Stewart1981TheMP,
  title={The MgATP-dependent protein phosphatase and protein phosphatase 1 have identical substrate specificities.},
  author={Andrea A. Stewart and Brian A. Hemmings and Philip J. Cohen and Jozef Goris and Wilfried Merlevede},
  journal={European journal of biochemistry},
  year={1981},
  volume={115 1},
  pages={197-205}
}
The MgATP-dependent phosphorylase phosphatase was found to have a broad substrate specificity. Its activity against all phosphoproteins tested was dependent upon preincubation with the activating factor FA and MgATP. The enzyme dephosphorylated and inactivated phosphorylase kinase and inhibitor 1, and dephosphorylated and activated glycogen synthase and acetyl-CoA carboxylase. Glycogen synthase was dephosphorylated at similar rates whether it had been phosphorylated by cyclic-AMP-dependent… CONTINUE READING