The metabolism of tumours
- O. Warburg
The studies to be presented are part of a series of investigations on the metabolism of the kidney in renal hypertenison. In a previous paper (1) it was reported that the oxygen consumption of kidney slices and the oxidative deamination of amino acids and amines of slices and of extracts of kidneys from hypertensive dogs were markedly decreased as compared with kidneys from normal dogs. In the present study, an examination has been made of the cytochrome c concentration, the activities of the cytochrome oxidase, and of the succlnic dehydrogenase systems in the kidneys of dogs with renal hypertension. The effect of tissue suspensions and extracts of kidneys from hypertensive dogs and of preparations containing renin on the activities of the respiratory enzymes was also studied?