The Mesothelioma and Radical surgery randomized controlled trial: the Mars feasibility study.

@article{Treasure2009TheMA,
  title={The Mesothelioma and Radical surgery randomized controlled trial: the Mars feasibility study.},
  author={Tom Treasure and David Waller and Carol Hui-Chen Tan and James Entwisle and Mary O'brien and Ken O'Byrne and Gill Thomas and Michael P Snee and James Spicer and David Landau and Lo{\"i}c Lang-Lazdunski and Judith Bliss and Clare Peckitt and Shaun Rogers and Erica Marriage N{\'e}e Denholm and Gillian Coombes and Mark Webster-Smith and Julian Peto},
  journal={Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer},
  year={2009},
  volume={4 10},
  pages={1254-8}
}
HYPOTHESIS The effectiveness of extrapleural pneumonectomy (EPP) to extend quality-adjusted survival in malignant pleural mesothelioma within multimodality treatment should be proven in a randomized controlled trial if this radical surgery is to be regarded as the standard of care. The question was whether randomization to surgery versus no surgery would be possible. METHODS The Mesothelioma and Radical Surgery trial was planned to randomize 50 patients to test feasibility. There was a two… CONTINUE READING
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