The Merkel Cell Polyomavirus and Its Involvement in Merkel Cell Carcinoma

  title={The Merkel Cell Polyomavirus and Its Involvement in Merkel Cell Carcinoma},
  author={Kyle T. Amber and Michael Patrick McLeod and Keyvan Nouri},
  journal={Dermatologic Surgery},
BACKGROUND The discovery of the Merkel cell polyomavirus (MCV) in a large number of Merkel cell carcinomas (MCCs) has led to many investigations into its potential role as an oncovirus. Many studies have recently explored the differences between MCCs infected and not infected with MCV. OBJECTIVE To review the role of MCV in MCC and its potential to influence diagnosis, prognosis, and treatment. METHODS AND MATERIALS An extensive literature search was performed on MCV and its relationship with… 

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