The Mechanism of the Topical Effect of Penicillin G in Experimental Local Streptococcal Infections *

@article{Grunberg1948TheMO,
  title={The Mechanism of the Topical Effect of Penicillin G in Experimental Local Streptococcal Infections *},
  author={Emanuel Grunberg and R. J. Schnitzer and C. Unger},
  journal={The Yale Journal of Biology and Medicine},
  year={1948},
  volume={20},
  pages={479 - 486}
}
In the course of studies on the topical activity of penicillin G, we were confronted with the problem of defining the mechanism of its antibacterial effect. The rapid absorption of aqueous penicillin solutions from the site of administration on one hand, and the local defense reaction toward a bacterial infection on the other hand seemed to require a two… CONTINUE READING