The Mechanism of insulin secretion after oral glucose administration

  title={The Mechanism of insulin secretion after oral glucose administration},
  author={Ulrich Fischer and Hendrik Hommel and Marc Zi{\'e}gler and Richard P. Michael},
In conscious trained dogs (Alsatians) the IRI-concentration in the peripheral venous blood after oral administration of glucose increases when the blood glucose is still unchanged. After one or two peaks during the first 20 min IRI increases parallel to the blood sugar increase. In relation to the intravenous injection of glucose the IRI maximum after oral administration occurs earlier. Furthermore the ratio of the IRI to blood sugar areas is raised. Without any blood sugar change the IRI… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 19 extracted citations

Aspects of the relationship between drug dose and drug effect.

Dose-response : a publication of International Hormesis Society • 2009

Disparate effects of infused nutrients on delayed glucoprivic feeding and hypothalamic norepinephrine turnover.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 1981
View 1 Excerpt


Publications referenced by this paper.
Showing 1-10 of 47 references

The effect of atropine on plasma gastrin response to feeding

J. H. Walsh, S. A. Berson
Gastroenterology • 1971

Blood sugar and serum I R I after oral and intravenous administrat ion of glucose in male wistar rats with portocaval anastomosis

Assal, J .P., R. Levrat, W. Stauffacher
Abstr. Diabetologia 6, 35 • 1970

Conditioned hypoglycemia: Pseudoconditioning controls.

Journal of comparative and physiological psychology • 1970

Conditioned insulin secretion in the albino rat.

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine • 1970

Difference in insulin and growth hormone secretion after intravenous and intraduodenal administration of mixed amino acids in humans

S. Raptis, K. E. Schrbder, +6 authors E. F. Pfeiffer
Abstr. Diabetologia 6, 61 • 1970

Similar Papers

Loading similar papers…