The Mechanism and Characterization of Learning and Memory Impairment in Sleep-Deprived Mice

Abstract

Objectives are to examine the effects of sleep deprivation (SD) on spatial learning and memory in mice, to determine how SD effects the expression of phosphorylated cyclic AMP responsive element binding protein (pCREB) in mouse hippocampus, and to explore the mechanism of influence of sleep deprivation on cognitive function. Twenty, 3-month-old female C57BL… (More)
DOI: 10.1007/s12013-010-9098-8

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