The Mechanical Environment of Bone Marrow: A Review

  title={The Mechanical Environment of Bone Marrow: A Review},
  author={Umut A. Gurkan and Ozan Akkus},
  journal={Annals of Biomedical Engineering},
Bone marrow is a viscous tissue that resides in the confines of bones and houses the vitally important pluripotent stem cells. Due to its confinement by bones, the marrow has a unique mechanical environment which has been shown to be affected from external factors, such as physiological activity and disuse. The mechanical environment of bone marrow can be defined by determining hydrostatic pressure, fluid flow induced shear stress, and viscosity. The hydrostatic pressure values of bone marrow… CONTINUE READING
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