The Mayo Clinic family study of Parkinson's disease: study design, instruments, and sample characteristics.

@article{Rocca2005TheMC,
  title={The Mayo Clinic family study of Parkinson's disease: study design, instruments, and sample characteristics.},
  author={Walter A. Rocca and Brett J. Peterson and Shannon K. McDonnell and James H. Bower and J. Eric Ahlskog and Daniel J. Schaid and Demetrius M. Maraganore},
  journal={Neuroepidemiology},
  year={2005},
  volume={24 3},
  pages={151-67}
}
We describe here the Mayo Clinic Family Study of Parkinson's disease (PD), including the overall study design (historical cohort study of relatives from birth to onset of PD or censoring), the data collection instruments, the strategies implemented to prevent or measure biases, and the sample obtained. These methodological details may provide assistance to other investigators designing studies of the familial aggregation of PD or other aging-related chronic diseases. We investigated the… CONTINUE READING

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